Ponericin-W1 (11-25) [P4K; S5K; G8K; K13L; Q15K], At3

General Information


DRACP ID  DRACP04550

Peptide Name   Ponericin-W1 (11-25) [P4K; S5K; G8K; K13L; Q15K], At3

Sequence  KLLKKVVKLFKKLLK

Sequence Length  15

UniProt ID  P82423 

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Acetylation

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C91H168N22O16

Absent amino acids  ACDEGHIMNPQRSTWY

Common amino acids  K

Mass  207638

Pl  11.58

Basic residues  7

Acidic residues  0

Hydrophobic residues  8

Net charge  7

Boman Index  -319

Hydrophobicity  19.33

Aliphatic Index  168.67

Half Life 
  Mammalian: 1.3 hour
  Yeast: 3 min
  E.coli: 2 min

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  0

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 36174494

Title  Anticancer effect of rationally designed δΌͺ-helical amphiphilic peptides

Doi Not available

Year  2022

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  20547

DRACP is developed by Dr.Zheng's team.