This work is licensed under a Creative Commons Attribution 4.0 International License.
Lasso peptide Felipeptin A2
General Information
DRACP ID DRACP04566
Peptide Name Lasso peptide Felipeptin A2
Sequence GGGGRGYEYNKQCLIFC
Sequence Length 17
UniProt ID Not available
PubChem CID Not available
Origin Bacteria
Type Native peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C81H121N23O24S2
Absent amino acids ADHMPSTVW
Common amino acids G
Mass 215069
Pl 8.21
Basic residues 2
Acidic residues 1
Hydrophobic residues 3
Net charge 1
Boman Index -1966
Hydrophobicity -43.53
Aliphatic Index 45.88
Half Life
Mammalian: 30 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 3105
Absorbance 280nm 194.06
Polar residues 10
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 33294793
Title Class IV Lasso Peptides Synergistically Induce Proliferation of Cancer Cells and Sensitize Them to Doxorubicin
Doi Not available
Year 2020
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 20591
This work is licensed under a Creative Commons Attribution 4.0 International License.