VW4

General Information


DRACP ID  DRACP04649

Peptide Name   VW4

Sequence  VKKWVKKWVKKWVKKA

Sequence Length  16

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C104H169N27O17

Absent amino acids  CDEFGHILMNPQRSTY

Common amino acids  K

Mass  233739

Pl  11.65

Basic residues  8

Acidic residues  0

Hydrophobic residues  8

Net charge  8

Boman Index  -1944

Hydrophobicity  -95.63

Aliphatic Index  78.75

Half Life 
  Mammalian: 100 hour
  Yeast: >20 hour
  E.coli: >10 hour

Extinction Coefficient cystines  16500

Absorbance 280nm  1100

Polar residues  0

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 34721331

Title  The Trp-rich Antimicrobial Amphiphiles With Intramolecular Aromatic Interactions for the Treatment of Bacterial Infection

Doi Not available

Year  2021

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  20761

DRACP is developed by Dr.Zheng's team.