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VW4
General Information
DRACP ID DRACP04649
Peptide Name VW4
Sequence VKKWVKKWVKKWVKKA
Sequence Length 16
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C104H169N27O17
Absent amino acids CDEFGHILMNPQRSTY
Common amino acids K
Mass 233739
Pl 11.65
Basic residues 8
Acidic residues 0
Hydrophobic residues 8
Net charge 8
Boman Index -1944
Hydrophobicity -95.63
Aliphatic Index 78.75
Half Life
Mammalian: 100 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 16500
Absorbance 280nm 1100
Polar residues 0
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 34721331
Title The Trp-rich Antimicrobial Amphiphiles With Intramolecular Aromatic Interactions for the Treatment of Bacterial Infection
Doi Not available
Year 2021
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 20761
This work is licensed under a Creative Commons Attribution 4.0 International License.