hBD-1

General Information


DRACP ID  DRACP04652

Peptide Name   hBD-1

Sequence  DHYNCVSSGGQCLYSACPIFTKIQGTCYRGKAKCCK

Sequence Length  36

UniProt ID  P60022  DEFB1_HUMAN  P61263  A4H1Z4 

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer



Structure Information


PDB ID  2NLC  1E4S  2NLG  2NLB  2NLH  2PLZ  1IJV  2NLD  2NLF  2NLQ  2NLE  1KJ5  2NLP  1IJU  2NLS 

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic 

Disulfide/Other Bond  Native peptide

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C167H262N48O50S6

Absent amino acids  EMW

Common amino acids  C

Mass  455906

Pl  8.61

Basic residues  6

Acidic residues  1

Hydrophobic residues  7

Net charge  5

Boman Index  -4714

Hydrophobicity  -27.22

Aliphatic Index  46.11

Half Life 
  Mammalian: 30 hour
  Yeast: >20 hour
  E.coli: >10 hour

Extinction Coefficient cystines  4845

Absorbance 280nm  138.43

Polar residues  19

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 7628632

Title  Not available

Doi Not available

Year  Not available

Literature 2

Pubmed ID 28856417

Title  Not available

Doi Not available

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Literature 3

Pubmed ID 23980689

Title  Not available

Doi Not available

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Literature 4

Pubmed ID 23389903

Title  Not available

Doi Not available

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Literature 5

Pubmed ID 22664071

Title  Not available

Doi Not available

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Literature 6

Pubmed ID 21672084

Title  Not available

Doi Not available

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Literature 7

Pubmed ID 18957441

Title  Not available

Doi Not available

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Literature 8

Pubmed ID 18809937

Title  Not available

Doi Not available

Year  Not available

Literature 9

Pubmed ID 18782756

Title  Not available

Doi Not available

Year  Not available

Literature 10

Pubmed ID 15245864

Title  Not available

Doi Not available

Year  Not available

Literature 11

Pubmed ID 15177279

Title  Not available

Doi Not available

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Literature 12

Pubmed ID 12825184

Title  Not available

Doi Not available

Year  Not available

Literature 13

Pubmed ID 11862391

Title  Not available

Doi Not available

Year  Not available

Literature 14

Pubmed ID 11741980

Title  Not available

Doi Not available

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Literature 15

Pubmed ID 11714914

Title  Not available

Doi Not available

Year  Not available

Literature 16

Pubmed ID 11486002

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DRAMP ID  DRAMP02722

CancerPPD ID  4434

DBAASP ID  8282

DRACP is developed by Dr.Zheng's team.