This work is licensed under a Creative Commons Attribution 4.0 International License.
Buforin-1
General Information
DRACP ID DRACP04654
Peptide Name Buforin-1
Sequence AGRGKQGGKVRAKAKTRSSRAGLQFPVGRVHRLLRKGNY
Sequence Length 39
UniProt ID P55897
PubChem CID Not available
Origin Bufo bufo
Type Native peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic
Disulfide/Other Bond Native peptide
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C184H318N70O47
Absent amino acids CDEIMW
Common amino acids GR
Mass 494096
Pl 12.91
Basic residues 13
Acidic residues 0
Hydrophobic residues 11
Net charge 13
Boman Index -12040
Hydrophobicity -99.23
Aliphatic Index 62.56
Half Life
Mammalian: 30 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 1490
Absorbance 280nm 39.21
Polar residues 12
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 8946958
Title Not available
Doi Not available
Year Not available
Literature 2
Pubmed ID 8573171
Title Not available
Doi Not available
Year Not available
Literature 3
Pubmed ID 30570475
Title Not available
Doi Not available
Year Not available
Literature 4
Pubmed ID 26091834
Title Not available
Doi Not available
Year Not available
Literature 5
Pubmed ID 23724649
Title Not available
Doi Not available
Year Not available
Literature 6
Pubmed ID 21672084
Title Not available
Doi Not available
Year Not available
Literature 7
Pubmed ID 10890923
Title Not available
Doi Not available
Year Not available
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DRAMP ID DRAMP01162
DBAASP ID 2158
This work is licensed under a Creative Commons Attribution 4.0 International License.