This work is licensed under a Creative Commons Attribution 4.0 International License.
Big defensin (RPD-1)
General Information
DRACP ID DRACP04674
Peptide Name Big defensin (RPD-1)
Sequence AVPDVAFNAYG
Sequence Length 11
UniProt ID P86316
PubChem CID Not available
Origin Halobacteroides halobius
Type Native peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic
Disulfide/Other Bond Native peptide
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C52H74N12O16
Absent amino acids CEHIKLMQRSTW
Common amino acids A
Mass 130179
Pl 3.75
Basic residues 0
Acidic residues 1
Hydrophobic residues 6
Net charge -1
Boman Index 193
Hydrophobicity 57.27
Aliphatic Index 80
Half Life
Mammalian: 0.8 hour
Yeast: 10 min
E.coli: >10 hour
Extinction Coefficient cystines 1490
Absorbance 280nm 149
Polar residues 3
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 14673509
Title Not available
Doi Not available
Year Not available
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DRAMP ID DRAMP02397
This work is licensed under a Creative Commons Attribution 4.0 International License.