This work is licensed under a Creative Commons Attribution 4.0 International License.
Nisin A
General Information
DRACP ID DRACP04677
Peptide Name Nisin A
Sequence ITSISLCTPGCKTGALMGCNMKTATCHCSIHVSK
Sequence Length 34
UniProt ID P13068
PubChem CID Not available
Origin Bacteria
Type Native peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic
Disulfide/Other Bond Native peptide
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C143H246N42O45S7
Absent amino acids DEFQRWY
Common amino acids CT
Mass 408702
Pl 8.52
Basic residues 5
Acidic residues 0
Hydrophobic residues 8
Net charge 5
Boman Index -1288
Hydrophobicity 41.47
Aliphatic Index 71.76
Half Life
Mammalian: 30 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 250
Absorbance 280nm 7.58
Polar residues 18
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 8454055
Title Not available
Doi Not available
Year Not available
Literature 2
Pubmed ID 8418850
Title Not available
Doi Not available
Year Not available
Literature 3
Pubmed ID 7689965
Title Not available
Doi Not available
Year Not available
Literature 4
Pubmed ID 5131162
Title Not available
Doi Not available
Year Not available
Literature 5
Pubmed ID 3141403
Title Not available
Doi Not available
Year Not available
Literature 6
Pubmed ID 29767501
Title Not available
Doi Not available
Year Not available
Literature 7
Pubmed ID 2493449
Title Not available
Doi Not available
Year Not available
Literature 8
Pubmed ID 1905517
Title Not available
Doi Not available
Year Not available
Literature 9
Pubmed ID 1765078
Title Not available
Doi Not available
Year Not available
Literature 10
Pubmed ID 16559344
Title Not available
Doi Not available
Year Not available
Literature 11
Pubmed ID 1575686
Title Not available
Doi Not available
Year Not available
Literature 12
Pubmed ID 15232069
Title Not available
Doi Not available
Year Not available
Literature 13
Pubmed ID 1482192
Title Not available
Doi Not available
Year Not available
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DRAMP ID DRAMP00036
This work is licensed under a Creative Commons Attribution 4.0 International License.