Pyrularia thionin

General Information


DRACP ID  DRACP04683

Peptide Name   Pyrularia thionin

Sequence  KSCCRNTWARNCYNVCRLPGTISREICAKKCDCKIISGTTCPSDYPK

Sequence Length  47

UniProt ID  P07504 

PubChem CID  Not available

Origin  Pyrularia pubera

Type  Native peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic 

Disulfide/Other Bond  Native peptide

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C220H362N68O67S8

Absent amino acids  FHMQ

Common amino acids  C

Mass  610887

Pl  8.78

Basic residues  9

Acidic residues  3

Hydrophobic residues  9

Net charge  6

Boman Index  -10905

Hydrophobicity  -51.06

Aliphatic Index  51.91

Half Life 
  Mammalian: 30 hour
  Yeast: >20 hour
  E.coli: >10 hour

Extinction Coefficient cystines  8980

Absorbance 280nm  195.22

Polar residues  23

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 3985614

Title  Not available

Doi Not available

Year  Not available

Literature 2

Pubmed ID 18957441

Title  Not available

Doi Not available

Year  Not available

Literature 3

Pubmed ID 15494403

Title  Not available

Doi Not available

Year  Not available

Literature 4

Pubmed ID 12586366

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




CancerPPD ID  4447

DBAASP ID  595

DRACP is developed by Dr.Zheng's team.