Nisin Z

General Information


DRACP ID  DRACP04695

Peptide Name   Nisin Z

Sequence  ITSISLCTPGCKTGALMGCNMKTATCNCSIHVSK

Sequence Length  34

UniProt ID  LANZ_LACLL  P29559 

PubChem CID  Not available

Origin  Lactococcus lactis

Type  Native peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer



Structure Information


PDB ID  1WCO 

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic 

Disulfide/Other Bond  Native peptide

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C141H245N41O46S7

Absent amino acids  DEFQRWY

Common amino acids  CT

Mass  406398

Pl  8.51

Basic residues  4

Acidic residues  0

Hydrophobic residues  8

Net charge  4

Boman Index  -1486

Hydrophobicity  40.59

Aliphatic Index  71.76

Half Life 
  Mammalian: 30 hour
  Yeast: >20 hour
  E.coli: >10 hour

Extinction Coefficient cystines  250

Absorbance 280nm  7.58

Polar residues  19

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 8439149

Title  Not available

Doi Not available

Year  Not available

Literature 2

Pubmed ID 7626780

Title  Not available

Doi Not available

Year  Not available

Literature 3

Pubmed ID 1935953

Title  Not available

Doi Not available

Year  Not available

Literature 4

Pubmed ID 15361862

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DRAMP ID  DRAMP00037

DRACP is developed by Dr.Zheng's team.