Viscotoxin A3
General Information
DRACP ID DRACP04696
Peptide Name Viscotoxin A3
Sequence KSCCPNTTGRNIYNACRLTGAPRPTCAKLSGCKIISGSTCPSDYPK
Sequence Length 46
UniProt ID P01538 THN3_VISAL
PubChem CID Not available
Origin Viscum album
Type Native peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic
Disulfide/Other Bond Native peptide
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C201H334N62O64S6
Absent amino acids EFHMQVW
Common amino acids C
Mass 563843
Pl 9.16
Basic residues 7
Acidic residues 1
Hydrophobic residues 8
Net charge 6
Boman Index -8426
Hydrophobicity -46.3
Aliphatic Index 48.91
Half Life
Mammalian: 20 hour
Yeast: 30 min
E.coli: >10 hour
Extinction Coefficient cystines 3355
Absorbance 280nm 74.56
Polar residues 25
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 5719166
Title Not available
Doi Not available
Year Not available
Literature 2
Pubmed ID 4941626
Title Not available
Doi Not available
Year Not available
Literature 3
Pubmed ID 18957441
Title Not available
Doi Not available
Year Not available
Literature 4
Pubmed ID 1710983
Title Not available
Doi Not available
Year Not available
Literature 5
Pubmed ID 10947973
Title Not available
Doi Not available
Year Not available
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DRAMP ID DRAMP00954
CancerPPD ID 4441