Viscotoxin B
General Information
DRACP ID DRACP04703
Peptide Name Viscotoxin B
Sequence KSCCPNTTGRNIYNTCRLGGGSRERCASLSGCKIISASTCPSDYPK
Sequence Length 46
UniProt ID P01536 THNB_VISAL P08943 P84186
PubChem CID Not available
Origin Viscum album
Type Native peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic
Disulfide/Other Bond Native peptide
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C197H328N64O67S6
Absent amino acids FHMQVW
Common amino acids S
Mass 566034
Pl 8.87
Basic residues 7
Acidic residues 2
Hydrophobic residues 7
Net charge 5
Boman Index -10554
Hydrophobicity -55
Aliphatic Index 46.74
Half Life
Mammalian: 1.3 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 3355
Absorbance 280nm 74.56
Polar residues 27
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 18957441
Title Not available
Doi Not available
Year Not available
Literature 2
Pubmed ID 1710983
Title Not available
Doi Not available
Year Not available
Literature 3
Pubmed ID 12733989
Title Not available
Doi Not available
Year Not available
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DRAMP ID DRAMP00955
CancerPPD ID 4446