This work is licensed under a Creative Commons Attribution 4.0 International License.
Microcin E492
General Information
DRACP ID DRACP04707
Peptide Name Microcin E492
Sequence GETDPNTQLLNDLGNNMAWGAALGAPGGLGSAALGAAGGALQTVGQGLIDHGPVNVFIPVLIGPSWNGSGSGYNSATSSSGSGS
Sequence Length 84
PubChem CID Not available
Origin Klebsiella pneumoniae
Type Native peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic
Disulfide/Other Bond Native peptide
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C342H532N98O118S
Absent amino acids CKR
Common amino acids G
Mass 941732
Pl 3.7
Basic residues 1
Acidic residues 4
Hydrophobic residues 29
Net charge -3
Boman Index -2400
Hydrophobicity 6.55
Aliphatic Index 81.43
Half Life
Mammalian: 4.4 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 12490
Absorbance 280nm 150.48
Polar residues 41
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 7682973
Title Not available
Doi Not available
Year Not available
Literature 2
Pubmed ID 6385903
Title Not available
Doi Not available
Year Not available
Literature 3
Pubmed ID 19884380
Title Not available
Doi Not available
Year Not available
Literature 4
Pubmed ID 18957441
Title Not available
Doi Not available
Year Not available
Literature 5
Pubmed ID 15102848
Title Not available
Doi Not available
Year Not available
Literature 6
Pubmed ID 12890026
Title Not available
Doi Not available
Year Not available
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DRAMP ID DRAMP00222
CancerPPD ID 4385
This work is licensed under a Creative Commons Attribution 4.0 International License.