This work is licensed under a Creative Commons Attribution 4.0 International License.
Granulysin
General Information
DRACP ID DRACP04716
Peptide Name Granulysin
Sequence GRDYRTCLTIVQKLKKMVDKPTQRSVSNAATRVCRTGRSRWRDVCRNFMRRYQSRVTQGLVAGETAQQICEDLRLCIPSTGPL
Sequence Length 83
UniProt ID P22749
PubChem CID Not available
Origin Homo sapiens
Type Native peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic
Disulfide/Other Bond Native peptide
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C402H679N135O119S7
Absent amino acids H
Common amino acids R
Mass 1099486
Pl 11.11
Basic residues 17
Acidic residues 6
Hydrophobic residues 22
Net charge 11
Boman Index -24811
Hydrophobicity -61.45
Aliphatic Index 71.57
Half Life
Mammalian: 30 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 8730
Absorbance 280nm 106.46
Polar residues 27
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 9756476
Title Not available
Doi Not available
Year Not available
Literature 2
Pubmed ID 27276051
Title Not available
Doi Not available
Year Not available
Literature 3
Pubmed ID 12488100
Title Not available
Doi Not available
Year Not available
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DRAMP ID DRAMP03557
This work is licensed under a Creative Commons Attribution 4.0 International License.