This work is licensed under a Creative Commons Attribution 4.0 International License.
Mouse beta-defensin-14
General Information
DRACP ID DRACP04733
Peptide Name Mouse beta-defensin-14
Sequence FLPKTLRKFFCRIRGGRCAVLNCLGKEEQIGRCSNSGRKCCRKKK
Sequence Length 45
PubChem CID Not available
Origin Colon
Type Native peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic
Disulfide/Other Bond Native peptide
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C221H380N76O56S6
Absent amino acids DHMWY
Common amino acids KR
Mass 597528
Pl 11.12
Basic residues 14
Acidic residues 2
Hydrophobic residues 11
Net charge 12
Boman Index -12841
Hydrophobicity -63.56
Aliphatic Index 60.67
Half Life
Mammalian: 1.3 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 375
Absorbance 280nm 8.52
Polar residues 16
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 20176896
Title Not available
Doi Not available
Year Not available
Literature 2
Pubmed ID 18332171
Title Not available
Doi Not available
Year Not available
Literature 3
Pubmed ID 18167348
Title Not available
Doi Not available
Year Not available
Literature 4
Pubmed ID 15489334
Title Not available
Doi Not available
Year Not available
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DRAMP ID DRAMP03379
DBAASP ID 917
This work is licensed under a Creative Commons Attribution 4.0 International License.