Cyclic [W(RW)4 ]-Dox

General Information


DRACP ID  DRACP04809

Peptide Name   Cyclic [W(RW)4 ]-Dox

Sequence  WRWRWRWRW

Sequence Length  9

UniProt ID  Not available

PubChem CID  Not available

Origin 

Type 

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic 

Disulfide/Other Bond  Native peptide

N-terminal Modification  Free

C-terminal Modification  Dox, Doxorubicin

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C79H100N26O10

Absent amino acids  ACDEFGHIKLMNPQSTVY

Common amino acids  W

Mass  171669

Pl  12.98

Basic residues  4

Acidic residues  0

Hydrophobic residues  5

Net charge  4

Boman Index  -4803

Hydrophobicity  -250

Aliphatic Index  0

Half Life 
  Mammalian: 100 hour
  Yeast: >20 hour
  E.coli: >10 hour

Extinction Coefficient cystines  27500

Absorbance 280nm  3437.5

Polar residues  0

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 23301519

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




CancerPPD ID  3157

CancerPPD ID  3158

CancerPPD ID  3159

CancerPPD ID  3160

DRACP is developed by Dr.Zheng's team.