Fibrinogen derived

General Information


DRACP ID  DRACP04821

Peptide Name   Fibrinogen derived

Sequence  ARPAKAAATQKKVERKAPDA

Sequence Length  20

UniProt ID  Not available

PubChem CID  Not available

Origin  Fibrinogen

Type  Synthetic peptide

Classification

  

Active ACP Cancer targeted peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  αvβ3

Affinity  Not available

Mechanism  Not available

Nature  Anticancer



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic 

Disulfide/Other Bond  Native peptide

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C90H159N31O27

Absent amino acids  CFGHILMNSWY

Common amino acids  A

Mass  244654

Pl  11.22

Basic residues  6

Acidic residues  2

Hydrophobic residues  8

Net charge  4

Boman Index  -5897

Hydrophobicity  -111

Aliphatic Index  49.5

Half Life 
  Mammalian: 4.4 hour
  Yeast: >20 hour
  E.coli: >10 hour

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  1

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 21470139

Title  Anti-angiogenic peptides for cancer therapeutics

Doi 10.2174/138920111796117300

Year  2011

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DRACP is developed by Dr.Zheng's team.