FSEC
General Information
DRACP ID DRACP04827
Peptide Name FSEC
Sequence CELDENNTPMC
Sequence Length 11
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic
Disulfide/Other Bond Native peptide
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C48H77N13O21S3
Absent amino acids AFGHIKQRSVWY
Common amino acids CEN
Mass 144695
Pl 3.42
Basic residues 0
Acidic residues 3
Hydrophobic residues 1
Net charge -3
Boman Index -2836
Hydrophobicity -82.73
Aliphatic Index 35.45
Half Life
Mammalian: 1.2 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 125
Absorbance 280nm 12.5
Polar residues 5
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 11311231
Title A small peptide derived from Flt-1 (VEGFR-1) functions as an angiogenic inhibitor
Doi 10.1016/s0014-5793(01)02314-6
Year 2001
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available