This work is licensed under a Creative Commons Attribution 4.0 International License.
Endostatin fragment IV, IVox
General Information
DRACP ID DRACP04828
Peptide Name Endostatin fragment IV, IVox
Sequence CETWRTETTGATGQASSLLSGRLLEQKAASCHNSYIVLCIENSFMTSFSK
Sequence Length 50
UniProt ID Not available
PubChem CID Not available
Origin Collagen XVIII
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic
Disulfide/Other Bond Native peptide
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C233H371N65O78S4
Absent amino acids DP
Common amino acids S
Mass 633331
Pl 7.18
Basic residues 5
Acidic residues 4
Hydrophobic residues 15
Net charge 1
Boman Index -7694
Hydrophobicity -15.2
Aliphatic Index 68.4
Half Life
Mammalian: 1.2 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 7115
Absorbance 280nm 145.2
Polar residues 23
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 21470139
Title Anti-angiogenic peptides for cancer therapeutics
Doi 10.2174/138920111796117300
Year 2011
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.