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C16S
General Information
DRACP ID DRACP04844
Peptide Name C16S
Sequence DFKLFAVTIKYR
Sequence Length 12
UniProt ID Not available
PubChem CID Not available
Origin Laminin
Type Synthetic peptide
Classification
Active ACP Cancer targeted peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target αvβ3, α5β1
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic
Disulfide/Other Bond Native peptide
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C73H113N17O17
Absent amino acids CEGHMNPQSW
Common amino acids FK
Mass 169719
Pl 10.25
Basic residues 3
Acidic residues 1
Hydrophobic residues 6
Net charge 2
Boman Index -1580
Hydrophobicity 17.5
Aliphatic Index 97.5
Half Life
Mammalian: 1.1 hour
Yeast: 3 min
E.coli: >10 hour
Extinction Coefficient cystines 1490
Absorbance 280nm 135.45
Polar residues 2
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 21470139
Title Anti-angiogenic peptides for cancer therapeutics
Doi 10.2174/138920111796117300
Year 2011
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.