C16Y
General Information
DRACP ID DRACP04845
Peptide Name C16Y
Sequence DFKLFAVYIKYR
Sequence Length 12
UniProt ID Not available
PubChem CID Not available
Origin Laminin
Type Synthetic peptide
Classification
Active ACP Cancer targeted peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target αvβ3, α5β1
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic
Disulfide/Other Bond Native peptide
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C78H115N17O17
Absent amino acids CEGHMNPQSTW
Common amino acids FKY
Mass 175926
Pl 9.93
Basic residues 3
Acidic residues 1
Hydrophobic residues 6
Net charge 2
Boman Index -1337
Hydrophobicity 12.5
Aliphatic Index 97.5
Half Life
Mammalian: 1.1 hour
Yeast: 3 min
E.coli: >10 hour
Extinction Coefficient cystines 2980
Absorbance 280nm 270.91
Polar residues 2
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 21470139
Title Anti-angiogenic peptides for cancer therapeutics
Doi 10.2174/138920111796117300
Year 2011
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available