This work is licensed under a Creative Commons Attribution 4.0 International License.
PEDF P18
General Information
DRACP ID DRACP04849
Peptide Name PEDF P18
Sequence DPFFKVPVNKLAAAVSNFGYDLYRVRSSTSPTTN
Sequence Length 34
UniProt ID Not available
PubChem CID Not available
Origin PEDF
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic
Disulfide/Other Bond Native peptide
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C171H261N45O51
Absent amino acids CEHIMQW
Common amino acids SV
Mass 435199
Pl 9.93
Basic residues 4
Acidic residues 2
Hydrophobic residues 12
Net charge 2
Boman Index -5858
Hydrophobicity -27.06
Aliphatic Index 65.88
Half Life
Mammalian: 1.1 hour
Yeast: 3 min
E.coli: >10 hour
Extinction Coefficient cystines 2980
Absorbance 280nm 90.3
Polar residues 13
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 21470139
Title Anti-angiogenic peptides for cancer therapeutics
Doi 10.2174/138920111796117300
Year 2011
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.