PEDF 34-mer fragment
General Information
DRACP ID DRACP04850
Peptide Name PEDF 34-mer fragment
Sequence DPFFKVPVNKLAAVSNFGYDLYRVRSSMSPTTN
Sequence Length 33
UniProt ID Not available
PubChem CID Not available
Origin PEDF
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic
Disulfide/Other Bond Native peptide
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C169H258N44O49S
Absent amino acids CEHIQW
Common amino acids SV
Mass 429316
Pl 9.93
Basic residues 4
Acidic residues 2
Hydrophobic residues 11
Net charge 2
Boman Index -5547
Hydrophobicity -25.45
Aliphatic Index 64.85
Half Life
Mammalian: 1.1 hour
Yeast: 3 min
E.coli: >10 hour
Extinction Coefficient cystines 2980
Absorbance 280nm 93.13
Polar residues 12
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 21470139
Title Anti-angiogenic peptides for cancer therapeutics
Doi 10.2174/138920111796117300
Year 2011
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available