hsurvivin

General Information


DRACP ID  DRACP04865

Peptide Name   hsurvivin

Sequence  FLKDHRISTFKNWPF

Sequence Length  15

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic 

Disulfide/Other Bond  Native peptide

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C94H134N24O21

Absent amino acids  ACEGMQVY

Common amino acids  F

Mass  218613

Pl  10.79

Basic residues  4

Acidic residues  1

Hydrophobic residues  6

Net charge  3

Boman Index  -3090

Hydrophobicity  -65.33

Aliphatic Index  52

Half Life 
  Mammalian: 1.1 hour
  Yeast: 3 min
  E.coli: 2 min

Extinction Coefficient cystines  5500

Absorbance 280nm  392.86

Polar residues  3

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 17142738

Title  Dendritic cell targeting of survivin protein in a xenogeneic form elicits strong CD4+ T cell immunity to mouse survivin

Doi 10.4049/jimmunol.177.12.8410

Year  2006

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DRACP is developed by Dr.Zheng's team.