This work is licensed under a Creative Commons Attribution 4.0 International License.
Endostatin peptide fragment I (180–199)
General Information
DRACP ID DRACP04866
Peptide Name Endostatin peptide fragment I (180–199)
Sequence FLSSRLQDLYSIVRRADRAA
Sequence Length 20
UniProt ID Not available
PubChem CID Not available
Origin Collagen XVIII
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic
Disulfide/Other Bond Native peptide
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C102H169N33O30
Absent amino acids CEGHKMNPTW
Common amino acids R
Mass 267675
Pl 10.99
Basic residues 4
Acidic residues 2
Hydrophobic residues 9
Net charge 2
Boman Index -6087
Hydrophobicity -19.5
Aliphatic Index 107.5
Half Life
Mammalian: 1.1 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 1490
Absorbance 280nm 78.42
Polar residues 4
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 21470139
Title Anti-angiogenic peptides for cancer therapeutics
Doi 10.2174/138920111796117300
Year 2011
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.