Semastatin-5A.1
General Information
DRACP ID DRACP04882
Peptide Name Semastatin-5A.1
Sequence GPWERCTAQCGGGIQARRR
Sequence Length 19
UniProt ID Not available
PubChem CID Not available
Origin Homo sapiens (Sema 5A)
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic
Disulfide/Other Bond Native peptide
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C85H140N34O25S2
Absent amino acids DFHKLMNSVY
Common amino acids GR
Mass 242363
Pl 10.46
Basic residues 4
Acidic residues 1
Hydrophobic residues 4
Net charge 3
Boman Index -6295
Hydrophobicity -106.32
Aliphatic Index 31.05
Half Life
Mammalian: 30 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 5625
Absorbance 280nm 312.5
Polar residues 7
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 18780781
Title A systematic methodology for proteome-wide identification of peptides inhibiting the proliferation and migration of endothelial cells
Year 2008
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available