Cartilostatin-2

General Information


DRACP ID  DRACP04884

Peptide Name   Cartilostatin-2

Sequence  GPWGPCSGSCGPGRRLRRR

Sequence Length  19

UniProt ID  Not available

PubChem CID  Not available

Origin  Homo sapiens (CILP-2)

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic 

Disulfide/Other Bond  Native peptide

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C84H139N35O22S2

Absent amino acids  ADEFHIKMNQTVY

Common amino acids  GR

Mass  237659

Pl  12.32

Basic residues  5

Acidic residues  0

Hydrophobic residues  2

Net charge  5

Boman Index  -6689

Hydrophobicity  -121.05

Aliphatic Index  20.53

Half Life 
  Mammalian: 30 hour
  Yeast: >20 hour
  E.coli: >10 hour

Extinction Coefficient cystines  5625

Absorbance 280nm  312.5

Polar residues  9

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 18780781

Title  A systematic methodology for proteome-wide identification of peptides inhibiting the proliferation and migration of endothelial cells

Doi 10.1073/pnas.0803241105

Year  2008

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DRACP is developed by Dr.Zheng's team.