This work is licensed under a Creative Commons Attribution 4.0 International License.
VEGFderived peptide
General Information
DRACP ID DRACP04921
Peptide Name VEGFderived peptide
Sequence KSVRGKGKGQKRKRKKSRYK
Sequence Length 20
UniProt ID Not available
PubChem CID Not available
Origin Exon 6a of VEGF gene
Type Synthetic peptide
Classification
Active ACP Cancer targeted peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target VEGFR2
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic
Disulfide/Other Bond Native peptide
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C103H191N41O25
Absent amino acids ACDEFHILMNPTW
Common amino acids K
Mass 274296
Pl 12.56
Basic residues 12
Acidic residues 0
Hydrophobic residues 1
Net charge 12
Boman Index -10970
Hydrophobicity -263
Aliphatic Index 14.5
Half Life
Mammalian: 1.3 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 1490
Absorbance 280nm 78.42
Polar residues 6
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 21470139
Title Anti-angiogenic peptides for cancer therapeutics
Doi 10.2174/138920111796117300
Year 2011
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.