Chemokinostatin-1

General Information


DRACP ID  DRACP04951

Peptide Name   Chemokinostatin-1

Sequence  NGREACLDPEAPMVQKIVQKMLKG

Sequence Length  24

UniProt ID  Not available

PubChem CID  Not available

Origin  CXCL1

Type  Synthetic peptide

Classification

  

Active ACP Cancer targeted peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  CXCR3

Affinity  Not available

Mechanism  Not available

Nature  Anticancer



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic 

Disulfide/Other Bond  Native peptide

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C113H195N33O34S3

Absent amino acids  FHSTWY

Common amino acids  K

Mass  306662

Pl  8.54

Basic residues  4

Acidic residues  3

Hydrophobic residues  7

Net charge  1

Boman Index  -3731

Hydrophobicity  -45

Aliphatic Index  81.25

Half Life 
  Mammalian: 1.4 hour
  Yeast: 3 min
  E.coli: >10 hour

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  4

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 21470139

Title  Anti-angiogenic peptides for cancer therapeutics

Doi 10.2174/138920111796117300

Year  2011

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DRACP is developed by Dr.Zheng's team.