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PF4 derived
General Information
DRACP ID DRACP04952
Peptide Name PF4 derived
Sequence NGRKISLDLRAPLYKKIIKKLLES
Sequence Length 24
UniProt ID Not available
PubChem CID Not available
Origin PF4
Type Synthetic peptide
Classification
Active ACP Cancer targeted peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target VEGF FGF2
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic
Disulfide/Other Bond Native peptide
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C128H226N36O33
Absent amino acids CFHMQTVW
Common amino acids KL
Mass 320786
Pl 11
Basic residues 7
Acidic residues 2
Hydrophobic residues 9
Net charge 5
Boman Index -4459
Hydrophobicity -40
Aliphatic Index 134.17
Half Life
Mammalian: 1.4 hour
Yeast: 3 min
E.coli: >10 hour
Extinction Coefficient cystines 1490
Absorbance 280nm 64.78
Polar residues 5
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 21470139
Title Anti-angiogenic peptides for cancer therapeutics
Doi 10.2174/138920111796117300
Year 2011
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.