Kunitz-type serine protease inhibitor PIVL

General Information


DRACP ID  DRACP04959

Peptide Name   Kunitz-type serine protease inhibitor PIVL

Sequence  QDRPKFCYLPADPAECNAYMPRFYYDSASNKCKEFIYGGCRGNANNFKNRAECRHTCVAS

Sequence Length  60

UniProt ID  I2G9B4 

PubChem CID  Not available

Origin  Macrovipera lebetina

Type  Native peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic 

Disulfide/Other Bond  Native peptide

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C297H442N88O89S7

Absent amino acids  W

Common amino acids  ACN

Mass  794628

Pl  8.37

Basic residues  10

Acidic residues  6

Hydrophobic residues  14

Net charge  4

Boman Index  -15558

Hydrophobicity  -84.67

Aliphatic Index  29.5

Half Life 
  Mammalian: >20 hour
  Yeast: >20 hour
  E.coli: ?

Extinction Coefficient cystines  7825

Absorbance 280nm  132.63

Polar residues  24

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 23262217

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DRAMP ID  DRAMP01274

DRACP is developed by Dr.Zheng's team.