This work is licensed under a Creative Commons Attribution 4.0 International License.
Flt1-12
General Information
DRACP ID DRACP04972
Peptide Name Flt1-12
Sequence RPFVEMYSEIPE
Sequence Length 12
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic
Disulfide/Other Bond Native peptide
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C68H101N15O21S
Absent amino acids ACDGHKLNQTW
Common amino acids E
Mass 169306
Pl 3.98
Basic residues 1
Acidic residues 3
Hydrophobic residues 3
Net charge -2
Boman Index -2460
Hydrophobicity -57.5
Aliphatic Index 56.67
Half Life
Mammalian: 1 hour
Yeast: 2 min
E.coli: 2 min
Extinction Coefficient cystines 1490
Absorbance 280nm 135.45
Polar residues 2
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 11311231
Title A small peptide derived from Flt-1 (VEGFR-1) functions as an angiogenic inhibitor
Doi 10.1016/s0014-5793(01)02314-6
Year 2001
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.