Adamtsostatin-18

General Information


DRACP ID  DRACP04982

Peptide Name   Adamtsostatin-18

Sequence  SKWSECSRTCGGGVKFQER

Sequence Length  19

UniProt ID  Not available

PubChem CID  Not available

Origin  Homo sapiens (ADAMTS-18)

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic 

Disulfide/Other Bond  Native peptide

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C89H141N29O29S2

Absent amino acids  ADHILMNPY

Common amino acids  GS

Mass  246662

Pl  8.82

Basic residues  4

Acidic residues  2

Hydrophobic residues  3

Net charge  2

Boman Index  -5814

Hydrophobicity  -107.89

Aliphatic Index  15.26

Half Life 
  Mammalian: 1.9 hour
  Yeast: >20 hour
  E.coli: >10 hour

Extinction Coefficient cystines  5625

Absorbance 280nm  312.5

Polar residues  9

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 18780781

Title  A systematic methodology for proteome-wide identification of peptides inhibiting the proliferation and migration of endothelial cells

Doi 10.1073/pnas.0803241105

Year  2008

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DRACP is developed by Dr.Zheng's team.