Cartilostatin-1

General Information


DRACP ID  DRACP04987

Peptide Name   Cartilostatin-1

Sequence  SPWSKCSAACGQTGVQTRTR

Sequence Length  20

UniProt ID  Not available

PubChem CID  Not available

Origin  Homo sapiens (CILP-1)

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic 

Disulfide/Other Bond  Native peptide

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C86H142N30O29S2

Absent amino acids  DEFHILMNY

Common amino acids  ST

Mass  246345

Pl  9.91

Basic residues  3

Acidic residues  0

Hydrophobic residues  4

Net charge  3

Boman Index  -4995

Hydrophobicity  -74.5

Aliphatic Index  24.5

Half Life 
  Mammalian: 1.9 hour
  Yeast: >20 hour
  E.coli: >10 hour

Extinction Coefficient cystines  5625

Absorbance 280nm  296.05

Polar residues  10

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 18780781

Title  A systematic methodology for proteome-wide identification of peptides inhibiting the proliferation and migration of endothelial cells

Doi 10.1073/pnas.0803241105

Year  2008

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DRACP is developed by Dr.Zheng's team.