Connectostatin
General Information
DRACP ID DRACP05008
Peptide Name Connectostatin
Sequence TEWSACSKTCGMGISTRV
Sequence Length 18
UniProt ID Not available
PubChem CID Not available
Origin Homo sapiens (CTGF)
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic
Disulfide/Other Bond Native peptide
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C78H129N23O27S3
Absent amino acids DFHLNPQY
Common amino acids ST
Mass 222060
Pl 8.23
Basic residues 2
Acidic residues 1
Hydrophobic residues 4
Net charge 1
Boman Index -2530
Hydrophobicity -3.89
Aliphatic Index 43.33
Half Life
Mammalian: 7.2 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 5625
Absorbance 280nm 330.88
Polar residues 10
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 18780781
Title A systematic methodology for proteome-wide identification of peptides inhibiting the proliferation and migration of endothelial cells
Year 2008
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available