Connectostatin

General Information


DRACP ID  DRACP05008

Peptide Name   Connectostatin

Sequence  TEWSACSKTCGMGISTRV

Sequence Length  18

UniProt ID  Not available

PubChem CID  Not available

Origin  Homo sapiens (CTGF)

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic 

Disulfide/Other Bond  Native peptide

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C78H129N23O27S3

Absent amino acids  DFHLNPQY

Common amino acids  ST

Mass  222060

Pl  8.23

Basic residues  2

Acidic residues  1

Hydrophobic residues  4

Net charge  1

Boman Index  -2530

Hydrophobicity  -3.89

Aliphatic Index  43.33

Half Life 
  Mammalian: 7.2 hour
  Yeast: >20 hour
  E.coli: >10 hour

Extinction Coefficient cystines  5625

Absorbance 280nm  330.88

Polar residues  10

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 18780781

Title  A systematic methodology for proteome-wide identification of peptides inhibiting the proliferation and migration of endothelial cells

Doi 10.1073/pnas.0803241105

Year  2008

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DRACP is developed by Dr.Zheng's team.