Netrinstatin-5C

General Information


DRACP ID  DRACP05009

Peptide Name   Netrinstatin-5C

Sequence  TEWSVCNSRCGRGYQKRTR

Sequence Length  19

UniProt ID  Not available

PubChem CID  Not available

Origin  Homo sapiens (UNC-5C)

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic 

Disulfide/Other Bond  Native peptide

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C93H151N35O29S2

Absent amino acids  ADFHILMP

Common amino acids  R

Mass  260878

Pl  10.45

Basic residues  5

Acidic residues  1

Hydrophobic residues  2

Net charge  4

Boman Index  -8549

Hydrophobicity  -153.68

Aliphatic Index  15.26

Half Life 
  Mammalian: 7.2 hour
  Yeast: >20 hour
  E.coli: >10 hour

Extinction Coefficient cystines  7115

Absorbance 280nm  395.28

Polar residues  10

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 18780781

Title  A systematic methodology for proteome-wide identification of peptides inhibiting the proliferation and migration of endothelial cells

Doi 10.1073/pnas.0803241105

Year  2008

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DRACP is developed by Dr.Zheng's team.