This work is licensed under a Creative Commons Attribution 4.0 International License.
Tetrastatin-2
General Information
DRACP ID DRACP05015
Peptide Name Tetrastatin-2
Sequence TLPFAYCNIHQVCHYAQRNDRSYWL
Sequence Length 25
UniProt ID Not available
PubChem CID Not available
Origin Homo sapiens (α4 CIV)
Type Synthetic peptide
Classification
Active ACP Cancer targeted peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target αvβ3
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic
Disulfide/Other Bond Native peptide
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C140H200N40O37S2
Absent amino acids EGKM
Common amino acids Y
Mass 352777
Pl 8.23
Basic residues 4
Acidic residues 1
Hydrophobic residues 8
Net charge 3
Boman Index -4834
Hydrophobicity -52.4
Aliphatic Index 66.4
Half Life
Mammalian: 7.2 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 10095
Absorbance 280nm 420.63
Polar residues 9
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 18780781
Title A systematic methodology for proteome-wide identification of peptides inhibiting the proliferation and migration of endothelial cells
Year 2008
Literature 2
Pubmed ID 21470139
Title Anti-angiogenic peptides for cancer therapeutics
Doi 10.2174/138920111796117300
Year 2011
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.