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P144
General Information
DRACP ID DRACP05019
Peptide Name P144
Sequence TSLDASIIWAMMQN
Sequence Length 14
UniProt ID Not available
PubChem CID Not available
Origin TGFβ Receptor
Type Synthetic peptide
Classification
Active ACP Cancer targeted peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target TGFβ
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic
Disulfide/Other Bond Native peptide
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C68H109N17O22S2
Absent amino acids CEFGHKPRVY
Common amino acids AIMS
Mass 181291
Pl 3.75
Basic residues 0
Acidic residues 1
Hydrophobic residues 6
Net charge -1
Boman Index -486
Hydrophobicity 46.43
Aliphatic Index 97.86
Half Life
Mammalian: 7.2 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 5500
Absorbance 280nm 423.08
Polar residues 4
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 21470139
Title Anti-angiogenic peptides for cancer therapeutics
Doi 10.2174/138920111796117300
Year 2011
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.