Thrombostatin con-6

General Information


DRACP ID  DRACP05031

Peptide Name   Thrombostatin con-6

Sequence  WTRCSSSCGRGVSVRSR

Sequence Length  17

UniProt ID  Not available

PubChem CID  Not available

Origin  Homo sapiens (TSRC-6)

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic 

Disulfide/Other Bond  Native peptide

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C74H126N30O24S2

Absent amino acids  ADEFHIKLMNPQY

Common amino acids  S

Mass  216966

Pl  12.02

Basic residues  4

Acidic residues  0

Hydrophobic residues  3

Net charge  4

Boman Index  -6440

Hydrophobicity  -64.71

Aliphatic Index  34.12

Half Life 
  Mammalian: 2.8 hour
  Yeast: 3 min
  E.coli: 2 min

Extinction Coefficient cystines  5625

Absorbance 280nm  351.56

Polar residues  10

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 18780781

Title  A systematic methodology for proteome-wide identification of peptides inhibiting the proliferation and migration of endothelial cells

Doi 10.1073/pnas.0803241105

Year  2008

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DRACP is developed by Dr.Zheng's team.