This work is licensed under a Creative Commons Attribution 4.0 International License.
KV11
General Information
DRACP ID DRACP05049
Peptide Name KV11
Sequence YTMNPRKLFDY
Sequence Length 11
UniProt ID Not available
PubChem CID Not available
Origin Kringle 5
Type Synthetic peptide
Classification
Active ACP Cancer targeted peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target cSrc ERK
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic
Disulfide/Other Bond Native peptide
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C67H98N16O18S
Absent amino acids ACEGHIQSVW
Common amino acids Y
Mass 162621
Pl 9.15
Basic residues 2
Acidic residues 1
Hydrophobic residues 2
Net charge 1
Boman Index -2843
Hydrophobicity -107.27
Aliphatic Index 35.45
Half Life
Mammalian: 2.8 hour
Yeast: 10 min
E.coli: 2 min
Extinction Coefficient cystines 2980
Absorbance 280nm 298
Polar residues 4
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 19515999
Title Inhibition of pathologic retinal neovascularization by a small peptide derived from human apolipoprotein(a)
Year 2009
Literature 2
Pubmed ID 21470139
Title Anti-angiogenic peptides for cancer therapeutics
Doi 10.2174/138920111796117300
Year 2011
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.