This work is licensed under a Creative Commons Attribution 4.0 International License.
Tat (43-60)
General Information
DRACP ID DRACP05051
Peptide Name Tat (43-60)
Sequence LGISYGRKKRRQRRRPPQ
Sequence Length 18
UniProt ID Not available
PubChem CID Not available
Origin Protein derived
Type Native peptide
Classification
Cancer targeted peptides Membrane-targeted Cell-penetrating peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Labelled with Cys-acetamidomethyl
C-terminal Modification Fluorescein maleimide
Other Modification None
Chiral L
Physicochemical Information
Formula C96H170N40O23
Absent amino acids ACDEFHMNTVW
Common amino acids R
Mass 255604
Pl 12.81
Basic residues 8
Acidic residues 0
Hydrophobic residues 2
Net charge 8
Boman Index -10352
Hydrophobicity -220
Aliphatic Index 43.33
Half Life
Mammalian: 2.8 hour
Yeast: 10 min
E.coli: 2 min
Extinction Coefficient cystines 1490
Absorbance 280nm 87.65
Polar residues 4
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 9188504
Title Not available
Doi Not available
Year Not available
Patent
Patent ID US6740524B1
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
Cppsite ID 1002
This work is licensed under a Creative Commons Attribution 4.0 International License.