This work is licensed under a Creative Commons Attribution 4.0 International License.
Ala50 substitution mutant of Tat (49-57)
General Information
DRACP ID DRACP05062
Peptide Name Ala50 substitution mutant of Tat (49-57)
Sequence RAKRRQRRR
Sequence Length 9
UniProt ID Not available
PubChem CID Not available
Origin Protein derived
Type Native peptide
Classification
Cancer targeted peptides Membrane-targeted Cell-penetrating peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification fluorescein with 6-aminohexanoic acid (Ahx) spacer
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C50H99N29O11
Absent amino acids CDEFGHILMNPSTVWY
Common amino acids R
Mass 142538
Pl 13.2
Basic residues 7
Acidic residues 0
Hydrophobic residues 1
Net charge 7
Boman Index -9880
Hydrophobicity -362.22
Aliphatic Index 11.11
Half Life
Mammalian: 4.4 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 0
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 11087855
Title Not available
Doi Not available
Year Not available
Patent
Patent ID US6593292B1
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
Cppsite ID 1015
This work is licensed under a Creative Commons Attribution 4.0 International License.