Ala50 substitution mutant of Tat (49-57)

General Information


DRACP ID  DRACP05062

Peptide Name   Ala50 substitution mutant of Tat (49-57)

Sequence  RAKRRQRRR

Sequence Length  9

UniProt ID  Not available

PubChem CID  Not available

Origin  Protein derived

Type  Native peptide

Classification

  

Cancer targeted peptides Membrane-targeted Cell-penetrating peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  fluorescein with 6-aminohexanoic acid (Ahx) spacer

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C50H99N29O11

Absent amino acids  CDEFGHILMNPSTVWY

Common amino acids  R

Mass  142538

Pl  13.2

Basic residues  7

Acidic residues  0

Hydrophobic residues  1

Net charge  7

Boman Index  -9880

Hydrophobicity  -362.22

Aliphatic Index  11.11

Half Life 
  Mammalian: 4.4 hour
  Yeast: >20 hour
  E.coli: >10 hour

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  0

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 11087855

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID US6593292B1

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




Cppsite ID  1015

DRACP is developed by Dr.Zheng's team.