kV25K mutant

General Information


DRACP ID  DRACP05316

Peptide Name   kV25K mutant

Sequence  GLPVCGETCVGGTCNTPGCTCSWPKCTRN

Sequence Length  29

UniProt ID  Not available

PubChem CID  Not available

Origin  Protein derived

Type  Native peptide

Classification

  

Cancer targeted peptides Membrane-targeted Cell-penetrating peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Cyclic

Disulfide/Other Bond  Not available

N-terminal Modification  Alexa-488

C-terminal Modification  Cyclization

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C118H190N36O40S6

Absent amino acids  ADFHIMQY

Common amino acids  C

Mass  344500

Pl  7.73

Basic residues  2

Acidic residues  1

Hydrophobic residues  4

Net charge  1

Boman Index  -2910

Hydrophobicity  -12.76

Aliphatic Index  33.45

Half Life 
  Mammalian: 30 hour
  Yeast: >20 hour
  E.coli: >10 hour

Extinction Coefficient cystines  5875

Absorbance 280nm  209.82

Polar residues  19

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 21873420

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




Cppsite ID  1801

DRACP is developed by Dr.Zheng's team.