R11-PKI

General Information


DRACP ID  DRACP05320

Peptide Name   R11-PKI

Sequence  RRRRRRRRRRRTYADFIASGRTGRRNAI

Sequence Length  28

UniProt ID  Not available

PubChem CID  Not available

Origin  Chimeric

Type  Native peptide

Classification

  

Cancer targeted peptides Membrane-targeted Cell-penetrating peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Rhodamine B

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C146H261N71O36

Absent amino acids  CEHKLMPQVW

Common amino acids  R

Mass  406886

Pl  13.06

Basic residues  14

Acidic residues  1

Hydrophobic residues  6

Net charge  13

Boman Index  -21279

Hydrophobicity  -203.93

Aliphatic Index  38.57

Half Life 
  Mammalian: 4.4 hour
  Yeast: >20 hour
  E.coli: >10 hour

Extinction Coefficient cystines  1490

Absorbance 280nm  55.19

Polar residues  7

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 15937518

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




Cppsite ID  1810

DRACP is developed by Dr.Zheng's team.