KLA-Pen

General Information


DRACP ID  DRACP05436

Peptide Name   KLA-Pen

Sequence  CRQIKIWFQNRRMKWKKKLAKLAKKLAKLAK

Sequence Length  31

UniProt ID  Not available

PubChem CID  Not available

Origin  Chimeric

Type  Native peptide

Classification

  

Cancer targeted peptides Membrane-targeted Cell-penetrating peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Acetylation

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C179H309N55O35S2

Absent amino acids  DEGHPSTVY

Common amino acids  K

Mass  439120

Pl  12.36

Basic residues  13

Acidic residues  0

Hydrophobic residues  13

Net charge  13

Boman Index  -6995

Hydrophobicity  -84.52

Aliphatic Index  88.39

Half Life 
  Mammalian: 1.2 hour
  Yeast: >20 hour
  E.coli: >10 hour

Extinction Coefficient cystines  11000

Absorbance 280nm  366.67

Polar residues  2

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 24796502

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




Cppsite ID  2234

DRACP is developed by Dr.Zheng's team.