NYAD-36

General Information


DRACP ID  DRACP05459

Peptide Name   NYAD-36

Sequence  ISFⓍELLDYYⓍESGS

Sequence Length  15

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Cancer targeted peptides Stapled Peptides Membrane-targeted Cell-penetrating peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Cyclic (Stapled)

Disulfide/Other Bond  Stapled: Ⓧ(4) and Ⓧ (11) are cross-linked by hydrocarbon stapling

N-terminal Modification  Acetylation

C-terminal Modification  Amidation

Other Modification  Ⓧ(4)=(S)-2-(4′-pentenyl)alanine; Ⓧ(11)=(R)-2-(7′-octenyl)alanine

Chiral  L



Physicochemical Information


Formula  C70H95N13O23

Absent amino acids  ACHKMNPQRTVW

Common amino acids  S

Mass  195648

Pl  3.42

Basic residues  0

Acidic residues  3

Hydrophobic residues  4

Net charge  -3

Boman Index  -1414

Hydrophobicity  -6.67

Aliphatic Index  78

Half Life 
  /

Extinction Coefficient cystines  2980

Absorbance 280nm  212.86

Polar residues  6

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 24237936

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




Cppsite ID  2261

DRACP is developed by Dr.Zheng's team.