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NYAD-66
General Information
DRACP ID DRACP05460
Peptide Name NYAD-66
Sequence ISFⓍELLDYYⓍED
Sequence Length 13
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer targeted peptides Stapled Peptides Membrane-targeted Cell-penetrating peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Cyclic (Stapled)
Disulfide/Other Bond Stapled: Ⓧ(4) and Ⓧ (11) are cross-linked by hydrocarbon stapling
N-terminal Modification Acetylation
C-terminal Modification Amidation
Other Modification Ⓧ(4)=(S)-2-(4′-pentenyl)alanine; Ⓧ(11)=(R)-2-(7′-octenyl)alanine
Chiral L
Physicochemical Information
Formula C66H87N11O21
Absent amino acids ACGHKMNPQRTVW
Common amino acids DELYX
Mass 180470
Pl 3.29
Basic residues 0
Acidic residues 4
Hydrophobic residues 4
Net charge -4
Boman Index -1700
Hydrophobicity -19.23
Aliphatic Index 90
Half Life
/
Extinction Coefficient cystines 2980
Absorbance 280nm 248.33
Polar residues 3
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 24237936
Title Not available
Doi Not available
Year Not available
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
Cppsite ID 2262
This work is licensed under a Creative Commons Attribution 4.0 International License.