This work is licensed under a Creative Commons Attribution 4.0 International License.
kEA2x1 (Kallikrein inhibitor with external arginines)
General Information
DRACP ID DRACP05532
Peptide Name kEA2x1 (Kallikrein inhibitor with external arginines)
Sequence XARCSDRFRNCPADEALCGR
Sequence Length 20
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer targeted peptides Membrane-targeted Cell-penetrating peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Cyclic
Disulfide/Other Bond All cysteines form disulfide bridges with the T3-scaffold.
N-terminal Modification FITC
C-terminal Modification Amidation
Other Modification X=Ahx, 6-aminohexanoic acid
Chiral L
Physicochemical Information
Formula C84H136N32O27S3
Absent amino acids HIKMQTVWY
Common amino acids R
Mass 257147
Pl 8.05
Basic residues 4
Acidic residues 3
Hydrophobic residues 5
Net charge 1
Boman Index -7586
Hydrophobicity -76.5
Aliphatic Index 34.5
Half Life
/
Extinction Coefficient cystines 125
Absorbance 280nm 6.58
Polar residues 6
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 24697151
Title Not available
Doi Not available
Year Not available
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
Cppsite ID 2374
This work is licensed under a Creative Commons Attribution 4.0 International License.