This work is licensed under a Creative Commons Attribution 4.0 International License.
MCoTI-M4
General Information
DRACP ID DRACP05594
Peptide Name MCoTI-M4
Sequence GGVCPKILRRCRRDSDCPGACICRGNGYCGSGSR
Sequence Length 34
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer targeted peptides Membrane-targeted Cell-penetrating peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Cyclic
Disulfide/Other Bond Cys4<--->Cys21; Cys11<--->Cys23; Cys11<--->Cys29; NCB: Gly1<--->Asp34
N-terminal Modification Conjugation with Alexa Flour 488
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C140H238N54O44S6
Absent amino acids EFHMQTW
Common amino acids G
Mass 416293
Pl 8.89
Basic residues 7
Acidic residues 2
Hydrophobic residues 5
Net charge 5
Boman Index -9462
Hydrophobicity -50.88
Aliphatic Index 45.88
Half Life
Mammalian: 30 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 1865
Absorbance 280nm 56.52
Polar residues 18
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 24985034
Title Not available
Doi Not available
Year Not available
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
Cppsite ID 2456
This work is licensed under a Creative Commons Attribution 4.0 International License.