MCoTI-M5

General Information


DRACP ID  DRACP05595

Peptide Name   MCoTI-M5

Sequence  GGVCPRILRRCRRDSDCPGACICRGNGYCGSGSK

Sequence Length  34

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Cancer targeted peptides Membrane-targeted Cell-penetrating peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Cyclic

Disulfide/Other Bond  Cys4<--->Cys21; Cys11<--->Cys23; Cys11<--->Cys29; NCB: Gly1<--->Asp34

N-terminal Modification  Conjugation with Alexa Flour 488

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C140H238N54O44S6

Absent amino acids  EFHMQTW

Common amino acids  G

Mass  416293

Pl  8.89

Basic residues  7

Acidic residues  2

Hydrophobic residues  5

Net charge  5

Boman Index  -9462

Hydrophobicity  -50.88

Aliphatic Index  45.88

Half Life 
  Mammalian: 30 hour
  Yeast: >20 hour
  E.coli: >10 hour

Extinction Coefficient cystines  1865

Absorbance 280nm  56.52

Polar residues  18

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 24985034

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




Cppsite ID  2457

DRACP is developed by Dr.Zheng's team.