This work is licensed under a Creative Commons Attribution 4.0 International License.
MAC-1-Sp3
General Information
DRACP ID DRACP06011
Peptide Name MAC-1-Sp3
Sequence GFGⓍALKⓍLKKVL
Sequence Length 13
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer targeted peptides Stapled Peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Chymotrypsin hydrolysis
Affinity Not available
Mechanism Resisting chymotrypsin hydrolysis
Nature Anticancer; Antimicrobial; Anti-hemolysis
Structure Information
Helicity Not available
Linear/Cyclic Cyclic (Stapled)
Disulfide/Other Bond Stapled: Ⓧ(4) and Ⓧ (8) are cross-linked by hydrocarbon stapling
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification Ⓧ=(2R)-2-amino-2-methyl-6-heptenoic acid
Chiral L
Physicochemical Information
Formula C57H96N14O10
Absent amino acids CDEHIMNPQRSTWY
Common amino acids KL
Mass 135171
Pl 11.1
Basic residues 3
Acidic residues 0
Hydrophobic residues 6
Net charge 3
Boman Index 882
Hydrophobicity 59.23
Aliphatic Index 120
Half Life
/
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 2
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID CN113896766A
Patent Title Novel anti-tumor cyclic peptide active molecule, preparation method and application
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.